A Medical Research Evening at Remuera Golf Club. We welcomed Sryana Sukhdev and Dr Helen Murray to our meeting. Both speakers engaged impresed the audience with the work they are doing in their respective fields. Sryana Sukhdev Sryana is a PHD candidate whose area of study is focused on finding effective stroke treatments and improving the lives of stroke patients. Her enqury was kicked off when her father suffered a stroke and seeing his experience left an indllible impact on her and became the catalyst for her studies.The current treatments for stroke patients aim to restore blood flow to the brain as quickly as possible. Preferably within 3-4 hours. In some cases that is not possible especially if the stroke patient is in a rural area. Sryana’s research involves investigating whether nebulised sodium nitrite can serve as a novel treatment in extending the treatment window available to stroke patients. Sryana proposes using nebulised sodium nitrite as a cost-effective way of delivering nitrous oxide to a patient, which has been shown to be safe and welltolerated by clinical populations and could be administered quickly after stroke onset by first responders. The hypothesis is this will selectively improve collateral blood flow to stroke-affected areas. Sryana’s preclinical work will help to determine the way it does this and refine optimal timing and dosage and lead to human studies of the cerebrovascular effects of sodium nitrite treatment in a 'stroke risk' cohort. Sryana’s aim is to build evidence to support future clinical trials for this process. |